Target RWE at ISPE 2025
Discover our activities and real-world evidence solutions at the ISPE Annual Meeting & Conference
Explore our Research at ISPE
Target RWE is attending the ISPE Annual Conference from August 22-26, 2025 at the Walter E. Washington Convention Center in Washington DC.
With a strong focus on causal inference, modern epidemiological methods, and data-agnostic solutions, we continue to redefine how observational data is used to inform healthcare decisions and regulatory-grade evidence generation. Our presence includes a featured symposium and two poster presentations showcasing real-world applications of advanced causal methods—underscoring our leadership in turning complex methodologies into practical, impactful insights. Visit us at Booth #209 to learn more about our work and explore opportunities to collaborate.
Target RWE Research & Presentations at ISPE
Symposium
Integrating Real-World Data with Randomized Controlled Trials: Advancing Evidence Generation
Sunday, August 24, 2025
1:30 PM - 3:00 PM ET
This workshop will explore practical strategies for integrating Real-World Data (RWD) with Randomized Controlled Trials (RCTs) to strengthen evidence generation for regulatory, clinical, and research applications. With presentations from international experts and case studies spanning oncology and cardiovascular interventions, attendees will learn methods for designing external control arms, ensuring relevance and reliability of data integration, and extending trial results to broader patient populations.
Oral Presentation
Estimating Artificial Censoring Weights for Clone Censor Weighting Studies: Techniques and Lessons Learned
Sunday, August 24, 2025
12:00 PM - 1:30 PM ET
This oral presentation will focus on practical strategies for implementing clone censor weighting (CCW), a method used to estimate counterfactual outcomes under treatment protocols while addressing challenges such as immortal time bias. Emphasis will be placed on estimating artificial censoring weights—crucial for appropriately reweighting adherent patients.
Oral Presentation
Power vs. Precision When Estimating Risk Differences Using Observational Data: A Case Study from TARGET-IBD
Tuesday, August 26, 2025
12:00 PM - 1:30 PM ET
This oral presentation explores the challenges of applying traditional power-based sample size approaches to real-world observational studies, where sample sizes are fixed and confounding is often present. Using data from the Target RWE's IBD cohort, the study compares power and precision estimates for assessing the risk difference in surgery or hospitalization among patients who achieved early versus late disease remission.
Leadership and Expertise at ISPE
As Chief Scientific Officer of Target RWE, Jennifer Christian, PhD, MPH plays a vital leadership role not only within the organization, but also across the broader field of pharmacoepidemiology through her service to the International Society for Pharmacoepidemiology (ISPE). As an active member of ISPE’s Finance Committee, Dr. Christian brings both scientific and strategic acumen to the Society’s mission—ensuring rigorous fiscal oversight, transparency, and long-term sustainability. Her deep expertise in real-world evidence, combined with her operational leadership at Target RWE, positions her as a trusted advisor and influential contributor to ISPE’s financial governance. Her commitment to advancing evidence-based research and organizational integrity makes her an integral voice in shaping the future of pharmacoepidemiology.
2024 Research Presentations
Making the Case for Negative Control Outcome Studies in Real-World Evidence Research
David Pritchard, PhD, Director of Data Management & Statistics at Target RWE, shares a preview of his presentation for the DIA Real-World Evidence (RWE) Conference: "Making the Case for Negative Control Outcome Studies in a Real-World Evidence Setting." In this session, Dr. Pritchard explores the use of Negative Control Outcome (NCO) studies as a methodological strategy to enhance treatment group comparability—ultimately improving the validity and reliability of real-world research. Watch the video to learn how incorporating NCO studies can reduce bias, boost accuracy, and elevate the overall quality of your evidence.
Seeing Eye to Eye: Enhancing Inter-Team Communication for Reproducible Real-World Evidence
In this video, Nuvan Rathnayaka, Manager of Biostatistics at Target RWE, shares insights into this innovative approach and discusses how structured communication frameworks can improve the accuracy and reproducibility of real-world data analysis. Click the link to watch the video and learn more about the research, titled "Seeing Eye to Eye: Enhancing Inter-Team Communication for Reproducible Real-World Evidence."
