Published On: 8/27/2024

ISPE 2024 Research: Presentation by Kathleen Hurwitz ScD, Catherine Wiener, and Chase Latour

Team members Kathleen Hurwtiz, ScD, Catherine Wiener, and Chase Latour helped author a new Target RWE study presented at ISPE 2024 titled “Comparing causal estimands from a sequential nested trial emulation with a treatment decision design to a conventional single point randomized trial: A simulation study.”

The study investigates the potential biases in sequential nested trial emulations, a study designed for rare disease research. Using a simulation framework, the authors compared the results of sequential nested trial emulation to those of single-point randomized trials. Watch this research presentation for valuable insights on using sequential nested trial emulations, highlighting the importance of careful study design and analysis to ensure accurate results: